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Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells

BACKGROUND: Pharmacology-based target identification has become a novel strategy leading to the discovery of novel pathological biomarkers. Ellagic acid (EA), a dietary polyphenol compound, exhibits potent anticancer activities; however, the underlying mechanisms remain unclear. The current study so...

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Detalles Bibliográficos
Autores principales: Wang, Neng, Wang, Qi, Tang, Hailin, Zhang, Fengxue, Zheng, Yifeng, Wang, Shengqi, Zhang, Jin, Wang, Zhiyu, Xie, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712102/
https://www.ncbi.nlm.nih.gov/pubmed/29197410
http://dx.doi.org/10.1186/s13046-017-0635-9