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Alignment-free comparative genomic screen for structured RNAs using coarse-grained secondary structure dot plots

BACKGROUND: Structured non-coding RNAs play many different roles in the cells, but the annotation of these RNAs is lacking even within the human genome. The currently available computational tools are either too computationally heavy for use in full genomic screens or rely on pre-aligned sequences....

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Detalles Bibliográficos
Autores principales: Kato, Yuki, Gorodkin, Jan, Havgaard, Jakob Hull
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712110/
https://www.ncbi.nlm.nih.gov/pubmed/29197323
http://dx.doi.org/10.1186/s12864-017-4309-y