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Current status and perspectives of chimeric antigen receptor modified T cells for cancer treatment

Chimeric antigen receptor (CAR) is a recombinant immunoreceptor combining an antibody-derived targeting fragment with signaling domains capable of activating cells, which endows T cells with the ability to recognize tumor-associated surface antigens independent of the expression of major histocompat...

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Detalles Bibliográficos
Autores principales: Wang, Zhenguang, Guo, Yelei, Han, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712290/
https://www.ncbi.nlm.nih.gov/pubmed/28466386
http://dx.doi.org/10.1007/s13238-017-0400-z