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Current status and perspectives of chimeric antigen receptor modified T cells for cancer treatment
Chimeric antigen receptor (CAR) is a recombinant immunoreceptor combining an antibody-derived targeting fragment with signaling domains capable of activating cells, which endows T cells with the ability to recognize tumor-associated surface antigens independent of the expression of major histocompat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712290/ https://www.ncbi.nlm.nih.gov/pubmed/28466386 http://dx.doi.org/10.1007/s13238-017-0400-z |