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Indirubin Derivative 7-Bromoindirubin-3-Oxime (7Bio) Attenuates Aβ Oligomer-Induced Cognitive Impairments in Mice

Indirubins are natural occurring alkaloids extracted from indigo dye-containing plants. Indirubins could inhibit various kinases, and might be used to treat chronic myelocytic leukemia, cancer and neurodegenerative disorders. 7-bromoindirubin-3-oxime (7Bio), an indirubin derivative derived from indi...

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Detalles Bibliográficos
Autores principales: Chen, Liping, Huang, Chunhui, Shentu, Jieyi, Wang, Minjun, Yan, Sicheng, Zhou, Fei, Zhang, Zaijun, Wang, Chuang, Han, Yifan, Wang, Qinwen, Cui, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712304/
https://www.ncbi.nlm.nih.gov/pubmed/29234273
http://dx.doi.org/10.3389/fnmol.2017.00393