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Expression Optimization of Anti-CD22 scFv-Apoptin Fusion Protein Using Experimental Design Methodology
BACKGROUND: Design of experiments is a rapid and cost-effective approach for optimization of recombinant protein production process. In our previous study, we generated a potent dual-acting fusion protein, anti-CD22 scFv-apoptin, to target B-cell malignant cell lines. In the present investigation, w...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pasteur Institute
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712387/ https://www.ncbi.nlm.nih.gov/pubmed/28689385 http://dx.doi.org/10.22034/ibj.22.1.66 |