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Neoantigens Generated by Individual Mutations and Their Role in Cancer Immunity and Immunotherapy

Recent preclinical and clinical studies have proved the long-standing hypothesis that tumors elicit adaptive immune responses and that the antigens driving effective T-cell response are neoantigens, i.e., peptides that are generated from somatically mutated genes. Hence, the characterization of neoa...

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Detalles Bibliográficos
Autores principales: Efremova, Mirjana, Finotello, Francesca, Rieder, Dietmar, Trajanoski, Zlatko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712389/
https://www.ncbi.nlm.nih.gov/pubmed/29234329
http://dx.doi.org/10.3389/fimmu.2017.01679