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Neoantigens Generated by Individual Mutations and Their Role in Cancer Immunity and Immunotherapy
Recent preclinical and clinical studies have proved the long-standing hypothesis that tumors elicit adaptive immune responses and that the antigens driving effective T-cell response are neoantigens, i.e., peptides that are generated from somatically mutated genes. Hence, the characterization of neoa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712389/ https://www.ncbi.nlm.nih.gov/pubmed/29234329 http://dx.doi.org/10.3389/fimmu.2017.01679 |