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Cytochrome b5 protects photoreceptors from light stress-induced lipid peroxidation and retinal degeneration

Lipid peroxides are generated by oxidative stress in cells, and contribute to ageing and neurodegenerative disease. The eye is at special risk for lipid peroxidation because photoreceptors possess amplified sensory membranes rich in peroxidation-susceptible polyunsaturated fatty acids. Light-induced...

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Detalles Bibliográficos
Autores principales: Chen, Xinping, Hall, Hana, Simpson, Jeffrey P., Leon-Salas, Walter D., Ready, Donald F., Weake, Vikki M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712525/
https://www.ncbi.nlm.nih.gov/pubmed/29214051
http://dx.doi.org/10.1038/s41514-017-0019-6