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A Novel TetR Family Transcriptional Regulator, CalR3, Negatively Controls Calcimycin Biosynthesis in Streptomyces chartreusis NRRL 3882

Calcimycin is a unique ionophoric antibiotic that is widely used in biochemical and pharmaceutical applications, but the genetic basis underlying the regulatory mechanisms of calcimycin biosynthesis are unclear. Here, we identified the calR3 gene, which encodes a novel TetR family transcriptional re...

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Detalles Bibliográficos
Autores principales: Gou, Lixia, Han, Tiesheng, Wang, Xiaoxia, Ge, Jingxuan, Liu, Wenxiu, Hu, Fen, Wang, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712553/
https://www.ncbi.nlm.nih.gov/pubmed/29238338
http://dx.doi.org/10.3389/fmicb.2017.02371