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Intermittent Fasting Protects against Alzheimer’s Disease Possible through Restoring Aquaporin-4 Polarity

The impairment of amyloid-β (Aβ) clearance in the brain plays a causative role in Alzheimer’s disease (AD). Polarity distribution of aquaporin-4 (AQP4) is important to remove Aβ from brain. AQP4 polarity can be influenced by the ratio of two AQP4 isoforms M1 and M23 (AQP4-M1/M23), however, it is unk...

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Detalles Bibliográficos
Autores principales: Zhang, Jingzhu, Zhan, Zhipeng, Li, Xinhui, Xing, Aiping, Jiang, Congmin, Chen, Yanqiu, Shi, Wanying, An, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712566/
https://www.ncbi.nlm.nih.gov/pubmed/29238290
http://dx.doi.org/10.3389/fnmol.2017.00395