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Association of HLA-A and HLA-B Alleles with Lamotrigine-Induced Cutaneous Adverse Drug Reactions in the Thai Population

Background: Lamotrigine (LTG) is commonly used for treatment of epilepsy and bipolar disorder. It is one of the common cause of cutaneous adverse drug reactions (CADR). Clinical symptoms of LTG-induced CADR range from maculopapular exanthema (MPE) to severe cutaneous adverse reactions (SCAR). This s...

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Detalles Bibliográficos
Autores principales: Koomdee, Napatrupron, Pratoomwun, Jirawat, Jantararoungtong, Thawinee, Theeramoke, Voralaksana, Tassaneeyakul, Wichittra, Klaewsongkram, Jettanong, Rerkpattanapipat, Ticha, Santon, Siwalee, Puangpetch, Apichaya, Intusoma, Utcharee, Tempark, Therdpong, Deesudchit, Tayard, Satapornpong, Patompong, Visudtibhan, Anannit, Sukasem, Chonlaphat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712579/
https://www.ncbi.nlm.nih.gov/pubmed/29238301
http://dx.doi.org/10.3389/fphar.2017.00879