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Design and Evaluation of Novel Polymyxin Fluorescent Probes

Polymyxins (polymyxin B and colistin) are cyclic lipopeptide antibiotics that serve as a last-line defence against Gram-negative “superbugs”. In the present study, two novel fluorescent polymyxin probes were designed through regio-selective modifications of the polymyxin B core structure at the N-te...

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Detalles Bibliográficos
Autores principales: Yun, Bo, Roberts, Kade D., Thompson, Philip E., Nation, Roger L., Velkov, Tony, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713106/
https://www.ncbi.nlm.nih.gov/pubmed/29137129
http://dx.doi.org/10.3390/s17112598