PI3K-Akt Signal Transduction Molecules Maybe Involved in Downregulation of Erythroblasts Apoptosis and Perifosine Increased Its Apoptosis in Chronic Mountain Sickness

BACKGROUND: Chronic mountain sickness (CMS) has a higher incidence in the plateau region. The one of its principal characters is excessive erythrocytosis. The PI3K-Akt pathway plays an important role in the process of erythropoiesis, and could downregulate apoptosis by regulating apoptosis-related m...

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Detalles Bibliográficos
Autores principales: Zhao, Chengyu, Li, Zhanquan, Ji, Linhua, Ma, Jie, Ge, Ri-Li, Cui, Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713146/
https://www.ncbi.nlm.nih.gov/pubmed/29176544
http://dx.doi.org/10.12659/MSM.905739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713146/
https://www.ncbi.nlm.nih.gov/pubmed/29176544
http://dx.doi.org/10.12659/MSM.905739

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