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Intrinsic ubiquitin E3 ligase activity of histone acetyltransferase Hbo1 for estrogen receptor α

Estrogen receptors (ER) are important transcription factors to relay signals from estrogen and to regulate proliferation of some of breast cancers. The cycling of estrogen-induced DNA binding and ubiquitin-linked proteolysis of ER potentiates ER-mediated transcription. Indeed, several transcriptiona...

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Detalles Bibliográficos
Autores principales: IIZUKA, Masayoshi, SUSA, Takao, TAMAMORI-ADACHI, Mimi, OKINAGA, Hiroko, OKAZAKI, Tomoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713178/
https://www.ncbi.nlm.nih.gov/pubmed/28769019
http://dx.doi.org/10.2183/pjab.93.030