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The Peptidylarginine Deiminase Inhibitor Cl-Amidine Suppresses Inducible Nitric Oxide Synthase Expression in Dendritic Cells

The conversion of peptidylarginine into peptidylcitrulline by calcium-dependent peptidylarginine deiminases (PADs) has been implicated in the pathogenesis of a number of diseases, identifying PADs as therapeutic targets for various diseases. The PAD inhibitor Cl-amidine ameliorates the disease cours...

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Detalles Bibliográficos
Autores principales: Jang, Byungki, Ishigami, Akihito, Kim, Yong-Sun, Choi, Eun-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713228/
https://www.ncbi.nlm.nih.gov/pubmed/29077055
http://dx.doi.org/10.3390/ijms18112258