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Development of A Chimeric Antigen Receptor Targeting C-Type Lectin-Like Molecule-1 for Human Acute Myeloid Leukemia

The treatment of patients with acute myeloid leukemia (AML) with targeted immunotherapy is challenged by the heterogeneity of the disease and a lack of tumor-exclusive antigens. Conventional immunotherapy targets for AML such as CD33 and CD123 have been proposed as targets for chimeric antigen recep...

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Detalles Bibliográficos
Autores principales: Laborda, Eduardo, Mazagova, Magdalena, Shao, Sida, Wang, Xinxin, Quirino, Herlinda, Woods, Ashley K., Hampton, Eric N., Rodgers, David T., Kim, Chan Hyuk, Schultz, Peter G., Young, Travis S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713229/
https://www.ncbi.nlm.nih.gov/pubmed/29077054
http://dx.doi.org/10.3390/ijms18112259