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Gastric Cancer Cell Glycosylation as a Modulator of the ErbB2 Oncogenic Receptor

Aberrant expression and hyperactivation of the human epidermal growth factor receptor 2 (ErbB2) constitute crucial molecular events underpinning gastric neoplastic transformation. Despite ErbB2 extracellular domain being a well-known target for glycosylation, its glycosylation profile and the molecu...

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Detalles Bibliográficos
Autores principales: Duarte, Henrique O., Balmaña, Meritxell, Mereiter, Stefan, Osório, Hugo, Gomes, Joana, Reis, Celso A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713232/
https://www.ncbi.nlm.nih.gov/pubmed/29143776
http://dx.doi.org/10.3390/ijms18112262