Efficient Generation of Genome-Modified Mice Using Campylobacter jejuni-Derived CRISPR/Cas

Mammalian zygote-mediated genome-engineering by Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)/Cas is currently used for the generation of genome-modified animals. Here, we report that a Campylobacter jejuni-derived orthologous CRISPR/Cas system recognizes a 5′-NNNVRYAC sequence a...

Descripción completa

Detalles Bibliográficos
Autores principales: Fujii, Wataru, Ikeda, Arisa, Sugiura, Koji, Naito, Kunihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713256/
https://www.ncbi.nlm.nih.gov/pubmed/29088065
http://dx.doi.org/10.3390/ijms18112286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713256/
https://www.ncbi.nlm.nih.gov/pubmed/29088065
http://dx.doi.org/10.3390/ijms18112286

Ejemplares similares