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Endothelial Mesenchymal Transition in Hypoxic Microvascular Endothelial Cells and Paracrine Induction of Cardiomyocyte Apoptosis Are Mediated via TGFβ(1)/SMAD Signaling

Cardiac remodeling plays a crucial role in the development of heart failure after mycocardial infarction. Besides cardiomyocytes, endothelial cells are recognized to contribute to cardiac remodeling. We now investigated processes of endothelial mesenchymal transition (EndoMT) in microvascular endoth...

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Detalles Bibliográficos
Autores principales: Sniegon, Isabella, Prieß, Mona, Heger, Jacqueline, Schulz, Rainer, Euler, Gerhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713260/
https://www.ncbi.nlm.nih.gov/pubmed/29088068
http://dx.doi.org/10.3390/ijms18112290