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Endothelial Mesenchymal Transition in Hypoxic Microvascular Endothelial Cells and Paracrine Induction of Cardiomyocyte Apoptosis Are Mediated via TGFβ(1)/SMAD Signaling
Cardiac remodeling plays a crucial role in the development of heart failure after mycocardial infarction. Besides cardiomyocytes, endothelial cells are recognized to contribute to cardiac remodeling. We now investigated processes of endothelial mesenchymal transition (EndoMT) in microvascular endoth...
Autores principales: | Sniegon, Isabella, Prieß, Mona, Heger, Jacqueline, Schulz, Rainer, Euler, Gerhild |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713260/ https://www.ncbi.nlm.nih.gov/pubmed/29088068 http://dx.doi.org/10.3390/ijms18112290 |
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