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The Emerging Role of the Major Histocompatibility Complex Class I in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting upper and lower motoneurons (MNs). The etiology of the disease is still unknown for most patients with sporadic ALS, while in 5–10% of the familial cases, several gene mutations have been linked to the disease. Mutati...

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Detalles Bibliográficos
Autores principales: Chiarotto, Gabriela Bortolança, Nardo, Giovanni, Trolese, Maria Chiara, França, Marcondes Cavalcante, Bendotti, Caterina, de Oliveira, Alexandre Leite Rodrigues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713268/
https://www.ncbi.nlm.nih.gov/pubmed/29104236
http://dx.doi.org/10.3390/ijms18112298