Heparan Sulfate Biosynthetic System Is Inhibited in Human Glioma Due to EXT1/2 and HS6ST1/2 Down-Regulation

Heparan sulfate (HS) is an important component of the extracellular matrix and cell surface, which plays a key role in cell–cell and cell–matrix interactions. Functional activity of HS directly depends on its structure, which determined by a complex system of HS biosynthetic enzymes. During malignan...

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Detalles Bibliográficos
Autores principales: Ushakov, Victor S., Tsidulko, Alexandra Y., de La Bourdonnaye, Gabin, Kazanskaya, Galina M., Volkov, Alexander M., Kiselev, Roman S., Kobozev, Vyacheslav V., Kostromskaya, Diana V., Gaytan, Alexey S., Krivoshapkin, Alexei L., Aidagulova, Svetlana V., Grigorieva, Elvira V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713271/
https://www.ncbi.nlm.nih.gov/pubmed/29104277
http://dx.doi.org/10.3390/ijms18112301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713271/
https://www.ncbi.nlm.nih.gov/pubmed/29104277
http://dx.doi.org/10.3390/ijms18112301

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