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Heparan Sulfate Biosynthetic System Is Inhibited in Human Glioma Due to EXT1/2 and HS6ST1/2 Down-Regulation
Heparan sulfate (HS) is an important component of the extracellular matrix and cell surface, which plays a key role in cell–cell and cell–matrix interactions. Functional activity of HS directly depends on its structure, which determined by a complex system of HS biosynthetic enzymes. During malignan...
Autores principales: | Ushakov, Victor S., Tsidulko, Alexandra Y., de La Bourdonnaye, Gabin, Kazanskaya, Galina M., Volkov, Alexander M., Kiselev, Roman S., Kobozev, Vyacheslav V., Kostromskaya, Diana V., Gaytan, Alexey S., Krivoshapkin, Alexei L., Aidagulova, Svetlana V., Grigorieva, Elvira V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713271/ https://www.ncbi.nlm.nih.gov/pubmed/29104277 http://dx.doi.org/10.3390/ijms18112301 |
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