Effect of Saturated Stearic Acid on MAP Kinase and ER Stress Signaling Pathways during Apoptosis Induction in Human Pancreatic β-Cells Is Inhibited by Unsaturated Oleic Acid

It has been shown that saturated fatty acids (FAs) have a detrimental effect on pancreatic β-cells function and survival, leading to apoptosis, whereas unsaturated FAs are well tolerated and are even capable of inhibiting the pro-apoptotic effect of saturated FAs. Molecular mechanisms of apoptosis i...

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Detalles Bibliográficos
Autores principales: Šrámek, Jan, Němcová-Fürstová, Vlasta, Pavlíková, Nela, Kovář, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713282/
https://www.ncbi.nlm.nih.gov/pubmed/29099080
http://dx.doi.org/10.3390/ijms18112313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713282/
https://www.ncbi.nlm.nih.gov/pubmed/29099080
http://dx.doi.org/10.3390/ijms18112313

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