G2/M-Phase Checkpoint Adaptation and Micronuclei Formation as Mechanisms That Contribute to Genomic Instability in Human Cells

One of the most common characteristics of cancer cells is genomic instability. Recent research has revealed that G2/M-phase checkpoint adaptation—entering mitosis with damaged DNA—contributes to genomic changes in experimental models. When cancer cells are treated with pharmacological concentrations...

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Detalles Bibliográficos
Autores principales: Kalsbeek, Danî, Golsteyn, Roy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713313/
https://www.ncbi.nlm.nih.gov/pubmed/29113112
http://dx.doi.org/10.3390/ijms18112344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713313/
https://www.ncbi.nlm.nih.gov/pubmed/29113112
http://dx.doi.org/10.3390/ijms18112344

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