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miR-1224-5p Mediates Mitochondrial Damage to Affect Silica-Induced Pulmonary Fibrosis by Targeting BECN1

Silicosis is associated with fibroblast proliferation and extracellular matrix deposition in lung tissues. The dysregulation of miR-1224-5p has been implicated in several human cancers; however, the expression and function of miR-1224-5p in silicosis is unknown. The mitochondrial dysfunctions play c...

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Detalles Bibliográficos
Autores principales: Wu, Qiuyun, Xu, Tiantian, Liu, Yi, Li, Yan, Yuan, Jiali, Yao, Wenxi, Xu, Qi, Yan, Weiwen, Ni, Chunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713326/
https://www.ncbi.nlm.nih.gov/pubmed/29112159
http://dx.doi.org/10.3390/ijms18112357