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Site-Directed Mutagenesis of the Fibronectin Domains in Insulin Receptor-Related Receptor

The orphan insulin receptor-related receptor (IRR), in contrast to its close homologs, the insulin receptor (IR) and insulin-like growth factor receptor (IGF-IR) can be activated by mildly alkaline extracellular medium. We have previously demonstrated that IRR activation is defined by its extracellu...

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Detalles Bibliográficos
Autores principales: Deyev, Igor E., Chachina, Natalia A., Zhevlenev, Egor S., Petrenko, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713427/
https://www.ncbi.nlm.nih.gov/pubmed/29156593
http://dx.doi.org/10.3390/ijms18112461