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Site-Directed Mutagenesis of the Fibronectin Domains in Insulin Receptor-Related Receptor
The orphan insulin receptor-related receptor (IRR), in contrast to its close homologs, the insulin receptor (IR) and insulin-like growth factor receptor (IGF-IR) can be activated by mildly alkaline extracellular medium. We have previously demonstrated that IRR activation is defined by its extracellu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713427/ https://www.ncbi.nlm.nih.gov/pubmed/29156593 http://dx.doi.org/10.3390/ijms18112461 |