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Clinical Significance of Measuring Global Hydroxymethylation of White Blood Cell DNA in Prostate Cancer: Comparison to PSA in a Pilot Exploratory Study

This is the first study investigating the clinical relevance of 5-hydroxymethylcytosine (5hmC) in genomic DNA from white blood cells (WBC) in the context of prostate cancer (PCa) and other prostate pathologies. Using an enzyme-linked immunosorbent assay, we identified significantly different distrib...

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Detalles Bibliográficos
Autores principales: Grelus, Alin, Nica, Dragos V., Miklos, Imola, Belengeanu, Valerica, Ioiart, Ioan, Popescu, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713431/
https://www.ncbi.nlm.nih.gov/pubmed/29156615
http://dx.doi.org/10.3390/ijms18112465