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Altered Aconitase 2 Activity in Huntington’s Disease Peripheral Blood Cells and Mouse Model Striatum

Huntington’s disease (HD) is caused by an unstable cytosine adenine guanine (CAG) trinucleotide repeat expansion encoding a polyglutamine tract in the huntingtin protein. Previously, we identified several up- and down-regulated protein molecules in the striatum of the Hdh((CAG)150) knock-in mice at...

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Detalles Bibliográficos
Autores principales: Chen, Chiung-Mei, Wu, Yih-Ru, Chang, Kuo-Hsuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713446/
https://www.ncbi.nlm.nih.gov/pubmed/29160844
http://dx.doi.org/10.3390/ijms18112480