Nitric Oxide Mediates Crosstalk between Interleukin 1β and WNT Signaling in Primary Human Chondrocytes by Reducing DKK1 and FRZB Expression

Interleukin 1 beta (IL1β) and Wingless-Type MMTV Integration Site Family (WNT) signaling are major players in Osteoarthritis (OA) pathogenesis. Despite having a large functional overlap in OA onset and development, the mechanism of IL1β and WNT crosstalk has remained largely unknown. In this study,...

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Detalles Bibliográficos
Autores principales: Zhong, Leilei, Schivo, Stefano, Huang, Xiaobin, Leijten, Jeroen, Karperien, Marcel, Post, Janine N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713457/
https://www.ncbi.nlm.nih.gov/pubmed/29165387
http://dx.doi.org/10.3390/ijms18112491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713457/
https://www.ncbi.nlm.nih.gov/pubmed/29165387
http://dx.doi.org/10.3390/ijms18112491

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