Approaches to ab initio molecular replacement of α-helical transmembrane proteins

α-Helical transmembrane proteins are a ubiquitous and important class of proteins, but present difficulties for crystallographic structure solution. Here, the effectiveness of the AMPLE molecular replacement pipeline in solving α-helical transmembrane-protein structures is assessed using a small lib...

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Detalles Bibliográficos
Autores principales: Thomas, Jens M. H., Simkovic, Felix, Keegan, Ronan, Mayans, Olga, Zhang, Chengxin, Zhang, Yang, Rigden, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2017
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713875/
https://www.ncbi.nlm.nih.gov/pubmed/29199978
http://dx.doi.org/10.1107/S2059798317016436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713875/
https://www.ncbi.nlm.nih.gov/pubmed/29199978
http://dx.doi.org/10.1107/S2059798317016436

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