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Transcriptional accuracy modeling suggests two-step proofreading by RNA polymerase
We suggest a novel two-step proofreading mechanism with two sequential rounds of proofreading selection in mRNA transcription. It is based on the previous experimental observations that the proofreading RNA polymerase cleaves off transcript fragments of at least 2 nt and that transcript elongation a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714138/ https://www.ncbi.nlm.nih.gov/pubmed/29036494 http://dx.doi.org/10.1093/nar/gkx849 |