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Signal recognition particle binds to translating ribosomes before emergence of a signal anchor sequence

The bacterial signal recognition particle (SRP) is part of the machinery that targets ribosomes synthesizing membrane proteins to membrane-embedded translocons co-translationally. Recognition of nascent membrane proteins occurs by virtue of a hydrophobic signal-anchor sequence (SAS) contained in the...

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Detalles Bibliográficos
Autores principales: Mercier, Evan, Holtkamp, Wolf, Rodnina, Marina V., Wintermeyer, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714171/
https://www.ncbi.nlm.nih.gov/pubmed/29149347
http://dx.doi.org/10.1093/nar/gkx888