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Dna2 initiates resection at clean DNA double-strand breaks

Nucleolytic resection of DNA double-strand breaks (DSBs) is essential for both checkpoint activation and homology-mediated repair; however, the precise mechanism of resection, especially the initiation step, remains incompletely understood. Resection of blocked ends with protein or chemical adducts...

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Detalles Bibliográficos
Autores principales: Paudyal, Sharad C., Li, Shan, Yan, Hong, Hunter, Tony, You, Zhongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714177/
https://www.ncbi.nlm.nih.gov/pubmed/28981724
http://dx.doi.org/10.1093/nar/gkx830