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Optimized light-inducible transcription in mammalian cells using Flavin Kelch-repeat F-box1/GIGANTEA and CRY2/CIB1

Light-inducible systems allow spatiotemporal control of a variety of biological activities. Here, we report newly optimized optogenetic tools to induce transcription with light in mammalian cells, using the Arabidopsis photoreceptor Flavin Kelch-repeat F-box 1 (FKF1) and its binding partner GIGANTEA...

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Detalles Bibliográficos
Autores principales: Quejada, Jose R., Park, Seon-Hye E., Awari, Daniel W., Shi, Fan, Yamamoto, Hannah E., Kawano, Fuun, Jung, Juergen C., Yazawa, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714181/
https://www.ncbi.nlm.nih.gov/pubmed/29040770
http://dx.doi.org/10.1093/nar/gkx804