Measuring deaminated nucleotide surveillance enzyme ITPA activity with an ATP-releasing nucleotide chimera

Nucleotide quality surveillance enzymes play important roles in human health, by detecting damaged molecules in the nucleotide pool and deactivating them before they are incorporated into chromosomal DNA or adversely affect metabolism. In particular, deamination of adenine moiety in (deoxy)nucleosid...

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Detalles Bibliográficos
Autores principales: Ji, Debin, Stepchenkova, Elena I., Cui, Jian, Menezes, Miriam R., Pavlov, Youri I., Kool, Eric T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714213/
https://www.ncbi.nlm.nih.gov/pubmed/29036687
http://dx.doi.org/10.1093/nar/gkx774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714213/
https://www.ncbi.nlm.nih.gov/pubmed/29036687
http://dx.doi.org/10.1093/nar/gkx774

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