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Cdk5rap1-mediated 2-methylthio-N(6)-isopentenyladenosine modification is absent from nuclear-derived RNA species
2-Methylthio-N(6)-isopentenyl modification of adenosine (ms(2)i(6)A) is an evolutionally conserved modification that is found in transfer RNAs (tRNAs). We have recently shown that Cdk5 regulatory subunit-associated protein 1 (Cdk5rap1) specifically converts i(6)A to ms(2)i(6)A at position A37 of fou...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714233/ https://www.ncbi.nlm.nih.gov/pubmed/28981754 http://dx.doi.org/10.1093/nar/gkx819 |