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Cdk5rap1-mediated 2-methylthio-N(6)-isopentenyladenosine modification is absent from nuclear-derived RNA species

2-Methylthio-N(6)-isopentenyl modification of adenosine (ms(2)i(6)A) is an evolutionally conserved modification that is found in transfer RNAs (tRNAs). We have recently shown that Cdk5 regulatory subunit-associated protein 1 (Cdk5rap1) specifically converts i(6)A to ms(2)i(6)A at position A37 of fou...

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Detalles Bibliográficos
Autores principales: Fakruddin, Md., Wei, Fan Yan, Emura, Shohei, Matsuda, Shigeru, Yasukawa, Takehiro, Kang, Dongchon, Tomizawa, Kazuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714233/
https://www.ncbi.nlm.nih.gov/pubmed/28981754
http://dx.doi.org/10.1093/nar/gkx819