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Type 1 diabetes alters lipid handling and metabolism in human fibroblasts and peripheral blood mononuclear cells

Triggers of the autoimmune response that leads to type 1 diabetes (T1D) remain poorly understood. A possibility is that parallel changes in both T cells and target cells provoke autoimmune attack. We previously documented greater Ca(2+) transients in fibroblasts from T1D subjects than non-T1D after...

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Detalles Bibliográficos
Autores principales: Jones IV, Albert R., Coleman, Emily L., Husni, Nicholas R., Deeney, Jude T., Raval, Forum, Steenkamp, Devin, Dooms, Hans, Nikolajczyk, Barbara S., Corkey, Barbara E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714353/
https://www.ncbi.nlm.nih.gov/pubmed/29206239
http://dx.doi.org/10.1371/journal.pone.0188474