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Role of co-repressor genomic landscapes in shaping the Notch response

Repressors are frequently deployed to limit the transcriptional response to signalling pathways. For example, several co-repressors interact directly with the DNA-binding protein CSL and are proposed to keep target genes silenced in the absence of Notch activity. However, the scope of their contribu...

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Detalles Bibliográficos
Autores principales: Chan, Stephen K. K., Cerda-Moya, Gustavo, Stojnic, Robert, Millen, Kat, Fischer, Bettina, Fexova, Silvie, Skalska, Lenka, Gomez-Lamarca, Maria, Pillidge, Zoe, Russell, Steven, Bray, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714389/
https://www.ncbi.nlm.nih.gov/pubmed/29155828
http://dx.doi.org/10.1371/journal.pgen.1007096