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Role of co-repressor genomic landscapes in shaping the Notch response
Repressors are frequently deployed to limit the transcriptional response to signalling pathways. For example, several co-repressors interact directly with the DNA-binding protein CSL and are proposed to keep target genes silenced in the absence of Notch activity. However, the scope of their contribu...
Autores principales: | Chan, Stephen K. K., Cerda-Moya, Gustavo, Stojnic, Robert, Millen, Kat, Fischer, Bettina, Fexova, Silvie, Skalska, Lenka, Gomez-Lamarca, Maria, Pillidge, Zoe, Russell, Steven, Bray, Sarah J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714389/ https://www.ncbi.nlm.nih.gov/pubmed/29155828 http://dx.doi.org/10.1371/journal.pgen.1007096 |
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