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Progesterone impairs antigen-non-specific immune protection by CD8 T memory cells via interferon-γ gene hypermethylation

Pregnant women and animals have increased susceptibility to a variety of intracellular pathogens including Listeria monocytogenes (LM), which has been associated with significantly increased level of sex hormones such as progesterone. CD8 T memory(Tm) cell-mediated antigen-non-specific IFN-γ respons...

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Detalles Bibliográficos
Autores principales: Yao, Yushi, Li, Hui, Ding, Jie, Xia, Yixin, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714395/
https://www.ncbi.nlm.nih.gov/pubmed/29155896
http://dx.doi.org/10.1371/journal.ppat.1006736