Polygenicity and Epistasis Underlie Fitness-Proximal Traits in the Caenorhabditis elegans Multiparental Experimental Evolution (CeMEE) Panel

Understanding the genetic basis of complex traits remains a major challenge in biology. Polygenicity, phenotypic plasticity, and epistasis contribute to phenotypic variance in ways that are rarely clear. This uncertainty can be problematic for estimating heritability, for predicting individual pheno...

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Detalles Bibliográficos
Autores principales: Noble, Luke M., Chelo, Ivo, Guzella, Thiago, Afonso, Bruno, Riccardi, David D., Ammerman, Patrick, Dayarian, Adel, Carvalho, Sara, Crist, Anna, Pino-Querido, Ania, Shraiman, Boris, Rockman, Matthew V., Teotónio, Henrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714472/
https://www.ncbi.nlm.nih.gov/pubmed/29066469
http://dx.doi.org/10.1534/genetics.117.300406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714472/
https://www.ncbi.nlm.nih.gov/pubmed/29066469
http://dx.doi.org/10.1534/genetics.117.300406

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