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Caenorhabditis elegans BUB-3 and SAN-1/MAD3 Spindle Assembly Checkpoint Components Are Required for Genome Stability in Response to Treatment with Ionizing Radiation

Relatively little is known about the cross-talk between the spindle assembly checkpoint and the DNA damage response, especially in multicellular organisms. We performed a Caenorhabditis elegans forward genetic screen to uncover new genes involved in the repair of DNA damage induced by ionizing radia...

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Detalles Bibliográficos
Autores principales: Bertolini, Simone, Wang, Bin, Meier, Bettina, Hong, Ye, Gartner, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714485/
https://www.ncbi.nlm.nih.gov/pubmed/29046436
http://dx.doi.org/10.1534/g3.117.1122