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Dendritic Cells Transduced with Single Immunoglobulin IL-1-Related Receptor Exhibit Immature Properties and Prolong Islet Allograft Survival

Members of toll-like receptor-interleukin 1 receptor signaling [TLR/IL-1R (TIR)] superfamily mediate maturation of dendritic cells (DCs) and launch immune response in transplanted organs. In this study, we hypothesized that TIR8, also known as single immunoglobulin IL-1-related receptor (SIGIRR) mol...

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Detalles Bibliográficos
Autores principales: Xue, Zhicheng, Zhang, Xuzhi, Chen, Maogen, Lu, Xinjun, Deng, Ronghai, Ma, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714859/
https://www.ncbi.nlm.nih.gov/pubmed/29250066
http://dx.doi.org/10.3389/fimmu.2017.01671