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Dimensionality of Motion and Binding Valency Govern Receptor–Ligand Kinetics As Revealed by Agent-Based Modeling

Mathematical modeling and computer simulations have become an integral part of modern biological research. The strength of theoretical approaches is in the simplification of complex biological systems. We here consider the general problem of receptor–ligand binding in the context of antibody–antigen...

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Detalles Bibliográficos
Autores principales: Lehnert, Teresa, Figge, Marc Thilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714874/
https://www.ncbi.nlm.nih.gov/pubmed/29250071
http://dx.doi.org/10.3389/fimmu.2017.01692