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Modelling Torsade de Pointes arrhythmias in vitro in 3D human iPS cell-engineered heart tissue
Torsade de Pointes (TdP) is a lethal arrhythmia that is often drug-induced, thus there is an urgent need for development of models to test or predict the drug sensitivity of human cardiac tissue. Here, we present an in vitro TdP model using 3D cardiac tissue sheets (CTSs) that contain a mixture of h...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715012/ https://www.ncbi.nlm.nih.gov/pubmed/29057872 http://dx.doi.org/10.1038/s41467-017-01125-y |