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Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology
Organotypic co-cultures bridge the gap between standard two-dimensional culture and mouse models. Such assays increase the fidelity of pre-clinical studies, to better inform lead compound development and address the increasing attrition rates of lead compounds within the pharmaceutical industry, whi...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715059/ https://www.ncbi.nlm.nih.gov/pubmed/29203823 http://dx.doi.org/10.1038/s41598-017-17177-5 |