The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor

TFIIS-like transcript cleavage factors enhance the processivity and fidelity of archaeal and eukaryotic RNA polymerases. Sulfolobus solfataricus TFS1 functions as a bona fide cleavage factor, while the paralogous TFS4 evolved into a potent RNA polymerase inhibitor. TFS4 destabilises the TBP–TFB–RNAP...

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Detalles Bibliográficos
Autores principales: Fouqueau, Thomas, Blombach, Fabian, Hartman, Ross, Cheung, Alan C. M., Young, Mark J., Werner, Finn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715097/
https://www.ncbi.nlm.nih.gov/pubmed/29203770
http://dx.doi.org/10.1038/s41467-017-02081-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715097/
https://www.ncbi.nlm.nih.gov/pubmed/29203770
http://dx.doi.org/10.1038/s41467-017-02081-3

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