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Electro-osmotic capture and ionic discrimination of peptide and protein biomarkers with FraC nanopores
Biological nanopores are nanoscale sensors employed for high-throughput, low-cost, and long read-length DNA sequencing applications. The analysis and sequencing of proteins, however, is complicated by their folded structure and non-uniform charge. Here we show that an electro-osmotic flow through Fr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715100/ https://www.ncbi.nlm.nih.gov/pubmed/29038539 http://dx.doi.org/10.1038/s41467-017-01006-4 |