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A microsatellite repeat in PCA3 long non-coding RNA is associated with prostate cancer risk and aggressiveness

Short tandem repeats (STRs) are repetitive sequences of a polymorphic stretch of two to six nucleotides. We hypothesized that STRs are associated with prostate cancer development and/or progression. We undertook RNA sequencing analysis of prostate tumors and adjacent non-malignant cells to identify...

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Detalles Bibliográficos
Autores principales: Lai, John, Moya, Leire, An, Jiyuan, Hoffman, Andrea, Srinivasan, Srilakshmi, Panchadsaram, Janaththani, Walpole, Carina, Perry-Keene, Joanna L., Chambers, Suzanne, Lehman, Melanie L., Nelson, Colleen C., Clements, Judith A., Batra, Jyotsna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715103/
https://www.ncbi.nlm.nih.gov/pubmed/29203868
http://dx.doi.org/10.1038/s41598-017-16700-y